Barrier® BPC-GI

500 mcg BPC tablet

BPC tablet designed to support gut barrier function.

Barrier BPC-GI is a precision-pressed tablet that dissolves across the full 20 ft long GI tract.

Each bottle contains 60 count 500mcg tablets.

Supports digestive comfort and gut barrier integrity.
Designed to release BPC throughout the GI tract to support the gut lining
$119.00

BPC (as Pentadeca Short Chain Amino Acids)

A peptide native to the human GI system, designed to support normal gut barrier function.

Clean formulation:

Third-Party Tested
Made in USA
Vegan
Gluten Free
Soy Free
Dairy Free
100% Plant-Derived
No Synthetic Ingredients
No Artificial Fillers
Human-Grade Only

Take 1-2 tablets daily on an empty stomach, ideally 20-30 minutes before your first meal, or as directed by your healthcare professional.

  • Supports gut barrier integrity
  • Promotes healthy intestinal permeability
  • Supports healthy joint and soft tissue function
  • May help with digestive comfort and regularity
FINALLY, REAL RELIEF·JESSICA M GAME CHANGER FOR MY GUT HEALTH·DAVID R MADE DAILY DIGESTION FEEL EASIER·BRANDON S I FEEL LIKE A NEW PERSON·SARAH K THE ONE I KEEP COMING BACK TO·MICHAEL T INCREASED PERFORMANCE AND RECOVERY·MARISA P GAME CHANGER FOR YOUR ENERGY AND HEALTH·INES K MY STOMACH FINALLY FEELS NORMAL AGAIN·SAMSARA L MORE COMFORTABLE AFTER MEALS·NATALIE H MY DIGESTION HAS NEVER BEEN BETTER·RACHEL B WISH I FOUND THIS YEARS AGO·CHRIS W THE ONLY SUPPLEMENT THAT ACTUALLY DELIVERED·NATALIE HFINALLY, REAL RELIEF·JESSICA M GAME CHANGER FOR MY GUT HEALTH·DAVID R MADE DAILY DIGESTION FEEL EASIER·BRANDON S I FEEL LIKE A NEW PERSON·SARAH K THE ONE I KEEP COMING BACK TO·MICHAEL T INCREASED PERFORMANCE AND RECOVERY·MARISA P GAME CHANGER FOR YOUR ENERGY AND HEALTH·INES K MY STOMACH FINALLY FEELS NORMAL AGAIN·SAMSARA L MORE COMFORTABLE AFTER MEALS·NATALIE H MY DIGESTION HAS NEVER BEEN BETTER·RACHEL B WISH I FOUND THIS YEARS AGO·CHRIS W THE ONLY SUPPLEMENT THAT ACTUALLY DELIVERED·NATALIE H

The Gut Support Peptide

Peptides occur naturally throughout the body, helping regulate essential biological functions. But modern life can place extra stress on the systems that rely on them most.

BPC-GI is a dietary supplement made with BPC, a peptide sequence originally identified in human gastric juice and studied in relation to gut lining and normal gut barrier function.

Taken orally, BPC-GI is designed for GI-focused release to support digestive comfort, normal tissue function, and the gut lining your body relies on.

Gut barrier

The Gut Healing Peptide

Barrier BPC-GI Barrier® BPC-GI
Generic BPC Capsules Generic BPC Capsules
BPC Injections BPC Injections
Bovine Colostrum Bovine Colostrum
Probiotics Probiotics
Targets the gut barrier, a key foundation for digestive comfort & overall health
Designed for local release along the gut lining where support matters most
Engineered to distribute across entire GI tract
Made in the USA, Third party tested Unknown Unknown Sometimes Sometimes
Needle Free

Gut health starts with the barrier.

A one cell thick barrier. That's all that separates your bloodstream from bacteria, toxins, and undigested food.

When gut barrier function is under stress, digestive comfort and everyday resilience can be harder to support.

Probiotics, colostrum, and fiber all depend on the gut environment your barrier helps maintain.

BPC-GI was designed to support gut barrier function, digestive comfort, and everyday gut resilience.

Modern life can challenge your gut barrier

A healthy gut barrier

A healthy gut barrier.

A gut barrier under stress

Alcohol, highly processed foods, chronic stress, poor sleep, and antibiotics can all challenge normal gut barrier function over time.

Hour 1
Timeline
BPC-GI is designed to release throughout the GI tract, helping support the gut lining from the start.
Day 7
Timeline
Gut lining support begins to build. Digestion may start to feel calmer.
Day 30
Timeline
Continued gut barrier support for digestive comfort, skin health, and everyday energy.
Day 60
Timeline
Helps maintain healthy gut barrier function as comfort, skin, and energy support build.
Day 90+
Timeline
Long-term support for the gut barrier your body relies on every day.

Rigorous quality
standards

Safety comes first at Barrier. Our products are developed and tested to meet the most rigorous external standards.

Made in USA, FDA Registered, cGMP, Third Party Tested, COAs for Every Lot

Questions?
We have answers.

How should I take BPC-GI? +
Take one tablet daily on an empty stomach, ideally 20–30 minutes before your first meal. For best support, use consistently for at least 60 days.

Many practitioners suggest periodic use throughout the year to support gut barrier function, especially during seasons of travel, stress, alcohol use, or NSAID use.
When will I feel something? +
Some people notice early changes in digestive comfort within the first couple weeks. For best support, take BPC-GI consistently for at least 60 days.
What makes BPC-GI different from other BPC supplements? +
Many BPC supplements use standard capsules. BPC-GI uses a proprietary tablet designed for release throughout the GI tract to support the gut lining and normal barrier function.
Is Barrier labeled "research use only"? +
No. Barrier is human-grade with strict quality and testing standards.
Do you offer a money-back guarantee? +
Yes. We offer a 60-day satisfaction guarantee. If you don't notice a difference, contact us for a full refund.
View All
Is this the same as injectable BPC? +
BPC-GI uses BPC in an oral tablet format. It’s designed for GI-focused release to support gut barrier function.
How is BPC-GI tested? +

Every lot of BPC-GI is third-party tested for purity, potency, and safety before it ships. Testing includes identity confirmation, potency verification, endotoxin screening, microbial limits, and heavy metals analysis. Certificates of Analysis (COAs) are available on request.

Do I need a prescription? +
No. BPC-GI is available as a dietary supplement and does not require a prescription. However, we always recommend consulting with your healthcare provider before starting any new supplement.
Can I take BPC-GI with other supplements? +
Yes. BPC-GI can fit alongside many supplement routines. Because it focuses on gut barrier support, many people use it as a foundation for their broader digestive health stack.
Do I need to refrigerate my BPC-GI? +
No refrigeration required. Store tightly closed in a cool, dry place, away from heat, humidity, and direct sunlight.
Is BPC-GI safe to take while I'm pregnant or breastfeeding? +
As with any dietary supplement or new health protocol contemplated during pregnancy or lactation, we recommend speaking with your physician or obstetrician before you start consuming BPC-GI.
Which payment methods do you accept? +
We currently accept Visa, American Express, and Discover credit cards. Mastercard is not supported at this time.
Disclaimer +
Information on this site is for educational purposes only and is not medical advice. Our products are not intended to diagnose, treat, cure, or prevent any disease, and statements about them have not been evaluated by the FDA. Always consult a qualified healthcare professional before use, especially if you are pregnant, nursing, have a medical condition, or take medications; individual results may vary.
  • 5 stars: 115 (85%)
  • 4 stars: 14 (10%)
  • 3 stars: 3 (2%)
  • 2 stars: 1 (1%)
  • 1 star: 2 (1%)
R
Robert

The product worked for me. Took about 3 weeks. My issue was getting refills and shipping. I switched brands as they worked through “warehouse issues”. Their Zendesk CRM is like talking to Ai. Hopefully you have better luck.

M
Mike H.
Solid supplement

Consistently better over the last couple weeks. no complaints.

A
Amanda R.
Coffee doesn't wreck me anymore

I can drink my morning coffee without issues now. small thing but it's huge for me

T
Tommy F.
Does what it says

Bottle is smaller than I expected but the tablets are tiny so it makes sense. Digestion is better, recovery feels faster too.

R
Ryan C

I've had a fantastic experience with Barrier since starting with it a little over two months ago. I have a history of GI issues. I got my yearly colonoscopy almost two weeks ago and just got back the best results I've had in YEARS. No signs of active inflammation. On top of that, I just feel better globally. Oo knee pain after sports, no back stiffness in the mornings anymore, and just feeling better.Thank you Barrier!

S
Scott S

I'm really impressed with this product. For years my wife has been unable to digest dairy, and more recently raw vegetables. This made eating fresh food like salads impossible. After the first month with BPC-157 she's been able to re-introduce these foods into her diet. I can't tell you how miraculous that is after trying every probiotic/digestive aid on the market with minimal success. Barrier's customer service is top notch as well, and quickly answered any concerns I had with shipment.

F
Fred M.

My first order of Barrier BPC-157 arrived with an empty bottle due to what was clearly a rare manufacturing hiccup (a lot of cotton, no pills in the bottle!). These things happen, and while I was surprised, I was confident the company would make it right. They did. They responded almost immediately, communicated exceptionally well, and shipped a replacement right away. The new bottle arrived just as quickly as the original order. I was genuinely impressed with the professionalism and customer service. I've only been taking the BPC-157 for 3–4 days, but I've already noticed reduced acid reflux and stomach irritation. It's too early to judge the full results, but I'll update my review after completing the regimen. Overall, I was impressed by their customer service. This is not a fly-by-night company, but a thoughtful, customer-centric organization. Kudos to the team.

C
Clark Holden
Best Product Ever

This is literally the best product ever you have to try it

J
Jake H.
Actually works

I’ve tried a lot of gut supplements and this is the first one I’ve stuck with.

C
Cole T.
Better digestion

Simple and effective.

R
Ryan T.
Solid product

Easy to take and I actually feel a difference. Less gas and overall better digestion.

K
Kevin S.
Helps after meals

I used to feel heavy after eating. That feeling is mostly gone now.

S
Sean G.
Helped my stomach

Much less irritation after eating. Feels way better.

J
Josh F.
Less discomfort

Stomach issues have calmed down a lot.

M
Michael R.
Feeling better

Overall just feel better after meals.

K
Kyle A.
More comfortable

Stomach feels calmer.

M
Mark E.
More consistent

My stomach used to feel off randomly. Now it feels way more stable day to day.

Z
Zach P.
Great for gut

Really helps keep things stable.

M
Matt C.
Surprisingly effective

Didn’t expect to notice this much of a difference.

C
Chris M.
Didn’t expect this

Started for gut issues but my knee has been feeling better too. Pretty surprising.

A
Andrew S.
Works fast

Quick improvement in digestion.

E
Eric J.
Noticeable

Less bloating and more comfortable.

T
Tyler B.
Fast results

Started noticing changes in a few days. Pretty impressive.

D
David N.
Worth it

Definitely feels like it’s helping my gut.

B
Brandon Y.
Less bloating

Big improvement after meals.

D
Daniel R.
Big difference in digestion

Noticed way less bloating after meals within a few days. Feels like my stomach is finally calm again.

E
Ethan W.
Good for gut

Less discomfort and way less gas. Big win.

N
Nick D.
Feels clean

Hard to explain but digestion just feels smoother overall.

S
Spencer D.
Noticeable change

Clear difference in comfort.

B
Brian K.
Less bloating

Simple as that. Stomach feels flatter and less irritated.

L
Logan M.
Good product

Feels like it’s doing something.

J
Jason P.
Better than expected

Thought it would take weeks but noticed changes in under a week.

A
Alex V.
Good stuff

Does what it says. Digestion feels improved.

Barrier BPC-GI
BPC-GI 500 mcg BPC Tablet